STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioW6-carboxyhexanoate--CoA ligase; Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP. (266 aa)    
Predicted Functional Partners:
OGR34001.1
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
 
 0.998
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
  
 0.945
bioB
Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
 
  
 0.927
bioA
Adenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
 
 
 0.879
OGR34003.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.765
OGR34002.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.739
OGR29519.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.613
OGR33999.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.581
OGR33998.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.523
OGR32358.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.440
Your Current Organism:
Desulfuromonadales bacterium GWC26120
NCBI taxonomy Id: 1797916
Other names: D. bacterium GWC2_61_20, Desulfuromonadales bacterium GWC2_61_20
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.