OGR46518.1 protein (Elusimicrobia bacterium GWA25134)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

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[Homology]

Score

OGR46518.1

Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)

Predicted Functional Partners:

OGR50130.1

0.731

OGR50131.1

0.731

OGR47581.1

0.731

OGR46291.1

0.731

OGR45761.1

0.692

OGR47998.1

0.618

OGR48945.1

0.591

OGR46517.1

0.499

OGR47993.1

0.472

OGR48905.1

0.472

Your Current Organism:

Elusimicrobia bacterium GWA25134

NCBI taxonomy Id: 1797921
Other names: E. bacterium GWA2_51_34, Elusimicrobia bacterium GWA2_51_34

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OGR45761.1	OGR46518.1	A2X33_04835	A2X33_06235	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.692
OGR45761.1	OGR48945.1	A2X33_04835	A2X33_11010	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.825
OGR46291.1	OGR46518.1	A2X33_09740	A2X33_06235	Alpha-amylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.731
OGR46291.1	OGR48945.1	A2X33_09740	A2X33_11010	Alpha-amylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.541
OGR46517.1	OGR46518.1	A2X33_06230	A2X33_06235	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.499
OGR46518.1	OGR45761.1	A2X33_06235	A2X33_04835	Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.692
OGR46518.1	OGR46291.1	A2X33_06235	A2X33_09740	Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alpha-amylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.731
OGR46518.1	OGR46517.1	A2X33_06235	A2X33_06230	Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.499
OGR46518.1	OGR47581.1	A2X33_06235	A2X33_07670	Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alpha-1,4-glucan--maltose-1-phosphate maltosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.731
OGR46518.1	OGR47993.1	A2X33_06235	A2X33_01640	Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.472
OGR46518.1	OGR47998.1	A2X33_06235	A2X33_01665	Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.618
OGR46518.1	OGR48905.1	A2X33_06235	A2X33_10800	Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.472
OGR46518.1	OGR48945.1	A2X33_06235	A2X33_11010	Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.591
OGR46518.1	OGR50130.1	A2X33_06235	A2X33_05465	Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.731
OGR46518.1	OGR50131.1	A2X33_06235	A2X33_05470	Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.731
OGR47581.1	OGR46518.1	A2X33_07670	A2X33_06235	Alpha-1,4-glucan--maltose-1-phosphate maltosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.731
OGR47581.1	OGR48945.1	A2X33_07670	A2X33_11010	Alpha-1,4-glucan--maltose-1-phosphate maltosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.541
OGR47581.1	OGR50131.1	A2X33_07670	A2X33_05470	Alpha-1,4-glucan--maltose-1-phosphate maltosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.637
OGR47993.1	OGR46518.1	A2X33_01640	A2X33_06235	Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.472
OGR47993.1	OGR47998.1	A2X33_01640	A2X33_01665	Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.456

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Network Stats

number of nodes:

11

number of edges:

46

average node degree:

8.36

avg. local clustering coefficient:

0.921

expected number of edges:

45

PPI enrichment p-value:

0.441

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0007165

Signal transduction

8 of 345

1.32

1.75

5.80e-07

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016772

Transferase activity, transferring phosphorus-containing groups

9 of 616

1.12

1.35

7.02e-07

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

7 of 935

0.82

0.68

0.00090

GO:0016021

Integral component of membrane

9 of 1627

0.69

0.57

0.00061

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5063

Mixed, incl. Serpin, conserved site, and Two-component regulatory system

5 of 6

2.87

4.98

5.26e-10

CL:4333

PAS domain, and GAF-like domain superfamily

6 of 37

2.16

4.05

2.09e-09

CL:4344

PAS-associated, C-terminal, and PAS fold

4 of 11

2.51

3.59

1.30e-07

CL:4335

PAS-associated, C-terminal, and GAF-like domain superfamily

5 of 32

2.14

3.5

4.45e-08

CL:4348

PAS fold, and PAS fold-3

2 of 5

2.55

1.51

0.0017

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02020

Two-component system

8 of 826

0.94

0.91

4.63e-05

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0016020

Membrane

7 of 1188

0.72

0.44

0.0291

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0597

Phosphoprotein

7 of 181

1.54

2.39

5.75e-08

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000014

PAS domain

5 of 52

1.93

2.81

5.90e-07

IPR003661

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

7 of 123

1.71

2.79

4.09e-08

IPR036097

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily

7 of 129

1.69

2.75

4.09e-08

IPR035965

PAS domain superfamily

5 of 55

1.91

2.75

6.91e-07

IPR004358

Signal transduction histidine kinase-related protein, C-terminal

7 of 133

1.67

2.72

4.09e-08

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00388

His Kinase A (phosphoacceptor) domain

7 of 133

1.67

2.92

5.67e-09

SM00387

Histidine kinase-like ATPases

7 of 149

1.62

2.79

6.11e-09

SM00448

cheY-homologous receiver domain

7 of 173

1.56

2.58

1.12e-08

SM00091

PAS domain

4 of 47

1.88

2.31

9.09e-06

SM00086

Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)

3 of 34

1.9

1.73

0.00028

(more ...)

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