| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ORW99400.1 | ORX02856.1 | AWC30_16220 | AWC30_12295 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.895 |
| ORW99400.1 | ORX03474.1 | AWC30_16220 | AWC30_11295 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.991 |
| ORW99400.1 | ORX05791.1 | AWC30_16220 | AWC30_08150 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.929 |
| ORW99400.1 | ORX07294.1 | AWC30_16220 | AWC30_00670 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Sulfite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.403 |
| ORW99400.1 | ORX08019.1 | AWC30_16220 | AWC30_03650 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.875 |
| ORW99400.1 | ORX08453.1 | AWC30_16220 | AWC30_02130 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.861 |
| ORW99400.1 | cysM | AWC30_16220 | AWC30_16645 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase; Catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.712 |
| ORW99400.1 | dkgA | AWC30_16220 | AWC30_02125 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 2,5-diketo-D-gluconic acid reductase; Methylglyoxal reductase/beta-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.878 |
| ORW99400.1 | metE | AWC30_16220 | AWC30_08395 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.975 |
| ORW99400.1 | metK | AWC30_16220 | AWC30_03325 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.971 |
| ORX02856.1 | ORW99400.1 | AWC30_12295 | AWC30_16220 | Lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.895 |
| ORX02856.1 | ORX05791.1 | AWC30_12295 | AWC30_08150 | Lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.873 |
| ORX02856.1 | ORX07294.1 | AWC30_12295 | AWC30_00670 | Lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.895 |
| ORX02856.1 | ORX08019.1 | AWC30_12295 | AWC30_03650 | Lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.855 |
| ORX02856.1 | ORX08453.1 | AWC30_12295 | AWC30_02130 | Lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.819 |
| ORX02856.1 | cysM | AWC30_12295 | AWC30_16645 | Lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine synthase; Catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.638 |
| ORX02856.1 | metE | AWC30_12295 | AWC30_08395 | Lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.845 |
| ORX03474.1 | ORW99400.1 | AWC30_11295 | AWC30_16220 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.991 |
| ORX03474.1 | ORX05791.1 | AWC30_11295 | AWC30_08150 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.734 |
| ORX03474.1 | ORX08019.1 | AWC30_11295 | AWC30_03650 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.425 |