node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ORW99400.1 | ORX03468.1 | AWC30_16220 | AWC30_11140 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Asparagine synthetase B; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.410 |
ORW99400.1 | ORX04525.1 | AWC30_16220 | AWC30_09885 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.966 |
ORW99400.1 | ORX06709.1 | AWC30_16220 | AWC30_06310 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. | 0.917 |
ORW99400.1 | asd | AWC30_16220 | AWC30_06315 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.604 |
ORW99400.1 | dapF | AWC30_16220 | AWC30_14330 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.466 |
ORW99400.1 | thrB | AWC30_16220 | AWC30_09875 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.911 |
ORX03468.1 | ORW99400.1 | AWC30_11140 | AWC30_16220 | Asparagine synthetase B; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.410 |
ORX03468.1 | ORX04525.1 | AWC30_11140 | AWC30_09885 | Asparagine synthetase B; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.528 |
ORX03468.1 | ORX06709.1 | AWC30_11140 | AWC30_06310 | Asparagine synthetase B; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. | 0.893 |
ORX03468.1 | argG | AWC30_11140 | AWC30_04330 | Asparagine synthetase B; Derived by automated computational analysis using gene prediction method: Protein Homology. | Argininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.870 |
ORX03468.1 | lysA | AWC30_11140 | AWC30_09890 | Asparagine synthetase B; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.479 |
ORX04525.1 | ORW99400.1 | AWC30_09885 | AWC30_16220 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.966 |
ORX04525.1 | ORX03468.1 | AWC30_09885 | AWC30_11140 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Asparagine synthetase B; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.528 |
ORX04525.1 | ORX06709.1 | AWC30_09885 | AWC30_06310 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. | 0.997 |
ORX04525.1 | argG | AWC30_09885 | AWC30_04330 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Argininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.536 |
ORX04525.1 | asd | AWC30_09885 | AWC30_06315 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.988 |
ORX04525.1 | dapA | AWC30_09885 | AWC30_14480 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.923 |
ORX04525.1 | dapB | AWC30_09885 | AWC30_14545 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.716 |
ORX04525.1 | lysA | AWC30_09885 | AWC30_09890 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.985 |
ORX04525.1 | thrB | AWC30_09885 | AWC30_09875 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.999 |