node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AWC30_13790 | ORW99400.1 | AWC30_13790 | AWC30_16220 | Transposase; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.651 |
AWC30_13790 | ORX05791.1 | AWC30_13790 | AWC30_08150 | Transposase; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
AWC30_13790 | cysS | AWC30_13790 | AWC30_11925 | Transposase; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. | cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.541 |
AWC30_13790 | glyA | AWC30_13790 | AWC30_08225 | Transposase; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.953 |
AWC30_13790 | guaA | AWC30_13790 | AWC30_16835 | Transposase; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.766 |
ORW99290.1 | ORX05791.1 | AWC30_16650 | AWC30_08150 | Molybdopterin synthase sulfur carrier subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.970 |
ORW99400.1 | AWC30_13790 | AWC30_16220 | AWC30_13790 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Transposase; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.651 |
ORW99400.1 | ORX05791.1 | AWC30_16220 | AWC30_08150 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.929 |
ORW99400.1 | ORX05793.1 | AWC30_16220 | AWC30_08160 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.954 |
ORW99400.1 | ORX08453.1 | AWC30_16220 | AWC30_02130 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.861 |
ORW99400.1 | cysN | AWC30_16220 | AWC30_02535 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenylyltransferase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.638 |
ORW99400.1 | cysS | AWC30_16220 | AWC30_11925 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.713 |
ORW99400.1 | glyA | AWC30_16220 | AWC30_08225 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.919 |
ORW99400.1 | guaA | AWC30_16220 | AWC30_16835 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.737 |
ORW99400.1 | metZ | AWC30_16220 | AWC30_04950 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.949 |
ORX05791.1 | AWC30_13790 | AWC30_08150 | AWC30_13790 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transposase; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
ORX05791.1 | ORW99290.1 | AWC30_08150 | AWC30_16650 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molybdopterin synthase sulfur carrier subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.970 |
ORX05791.1 | ORW99400.1 | AWC30_08150 | AWC30_16220 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.929 |
ORX05791.1 | ORX05793.1 | AWC30_08150 | AWC30_08160 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
ORX05791.1 | ORX08453.1 | AWC30_08150 | AWC30_02130 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.956 |