STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDK84844.1Catabolite repression HPr-like protein. (92 aa)    
Predicted Functional Partners:
SDK83508.1
Phosphotransferase system, enzyme I, PtsI; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.994
SDK66747.1
PTS system, mannose-specific IIB component.
  
 0.985
SDK83608.1
PTS system, sucrose-specific IIC component.
  
 0.978
hprK
Hpr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...]
 
 
 
 0.876
SDK66668.1
PTS system, mannose-specific IID component.
    
 0.823
SDK66703.1
PTS system, mannose-specific IIC component.
    
 0.821
SDK38886.1
PTS HPr component phosphorylation site.
     
 0.785
SDL33127.1
PTS system, trehalose-specific IIC component.
  
 
 0.761
SDK26916.1
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
  
 
 0.736
SDK83563.1
Phosphocarrier protein.
  
     0.736
Your Current Organism:
Sarcina sp. DSM 11001
NCBI taxonomy Id: 1798184
Other names: S. sp. DSM 11001
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.