node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDR65573.1 | SDR77209.1 | SAMN04515667_0024 | SAMN04515667_0614 | HRDC domain-containing protein. | Hypothetical protein. | 0.879 |
SDR65573.1 | SDS25109.1 | SAMN04515667_0024 | SAMN04515667_1750 | HRDC domain-containing protein. | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.999 |
SDR65573.1 | polA | SAMN04515667_0024 | SAMN04515667_0241 | HRDC domain-containing protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.983 |
SDR65573.1 | rnhB | SAMN04515667_0024 | SAMN04515667_0035 | HRDC domain-containing protein. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.680 |
SDR65651.1 | rnhB | SAMN04515667_0036 | SAMN04515667_0035 | Hypothetical protein. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.737 |
SDR77209.1 | SDR65573.1 | SAMN04515667_0614 | SAMN04515667_0024 | Hypothetical protein. | HRDC domain-containing protein. | 0.879 |
SDR77209.1 | SDS25109.1 | SAMN04515667_0614 | SAMN04515667_1750 | Hypothetical protein. | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.995 |
SDR77209.1 | polA | SAMN04515667_0614 | SAMN04515667_0241 | Hypothetical protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.992 |
SDR77209.1 | rnhB | SAMN04515667_0614 | SAMN04515667_0035 | Hypothetical protein. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.722 |
SDR89290.1 | rnhB | SAMN04515667_0926 | SAMN04515667_0035 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.820 |
SDS15407.1 | SDS43973.1 | SAMN04515667_1531 | SAMN04515667_2182 | Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains. | 4Fe-4S dicluster domain-containing protein. | 0.997 |
SDS15407.1 | SDS47821.1 | SAMN04515667_1531 | SAMN04515667_2266 | Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains. | O-succinylbenzoic acid--CoA ligase. | 0.868 |
SDS15407.1 | rnhB | SAMN04515667_1531 | SAMN04515667_0035 | Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.725 |
SDS25109.1 | SDR65573.1 | SAMN04515667_1750 | SAMN04515667_0024 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | HRDC domain-containing protein. | 0.999 |
SDS25109.1 | SDR77209.1 | SAMN04515667_1750 | SAMN04515667_0614 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | Hypothetical protein. | 0.995 |
SDS25109.1 | polA | SAMN04515667_1750 | SAMN04515667_0241 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
SDS25109.1 | rnhB | SAMN04515667_1750 | SAMN04515667_0035 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.930 |
SDS25109.1 | thyA | SAMN04515667_1750 | SAMN04515667_0138 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.757 |
SDS43973.1 | SDS15407.1 | SAMN04515667_2182 | SAMN04515667_1531 | 4Fe-4S dicluster domain-containing protein. | Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains. | 0.997 |
SDS43973.1 | SDS47821.1 | SAMN04515667_2182 | SAMN04515667_2266 | 4Fe-4S dicluster domain-containing protein. | O-succinylbenzoic acid--CoA ligase. | 0.743 |