node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OGT45891.1 | OGT46538.1 | A3E83_02260 | A3E83_01370 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Protein TolA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.804 |
OGT46538.1 | OGT45891.1 | A3E83_01370 | A3E83_02260 | Protein TolA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.804 |
OGT46538.1 | cpoB | A3E83_01370 | A3E83_01385 | Protein TolA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | 0.721 |
OGT46538.1 | ffh | A3E83_01370 | A3E83_03045 | Protein TolA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 0.613 |
OGT46538.1 | guaA | A3E83_01370 | A3E83_03000 | Protein TolA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.763 |
OGT46538.1 | secA | A3E83_01370 | A3E83_02195 | Protein TolA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.625 |
OGT46538.1 | secE | A3E83_01370 | A3E83_03950 | Protein TolA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | tRNA-Trp; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.612 |
OGT46538.1 | secY | A3E83_01370 | A3E83_03485 | Protein TolA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.627 |
OGT46538.1 | tolB | A3E83_01370 | A3E83_01375 | Protein TolA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.935 |
OGT46538.1 | tolQ | A3E83_01370 | A3E83_01360 | Protein TolA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.884 |
OGT46538.1 | tolR | A3E83_01370 | A3E83_01365 | Protein TolA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.928 |
cpoB | OGT46538.1 | A3E83_01385 | A3E83_01370 | Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | Protein TolA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.721 |
cpoB | tolB | A3E83_01385 | A3E83_01375 | Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.960 |
cpoB | tolQ | A3E83_01385 | A3E83_01360 | Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.841 |
cpoB | tolR | A3E83_01385 | A3E83_01365 | Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | Protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.798 |
ffh | OGT46538.1 | A3E83_03045 | A3E83_01370 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | Protein TolA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.613 |
ffh | secA | A3E83_03045 | A3E83_02195 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.706 |
ffh | secE | A3E83_03045 | A3E83_03950 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | tRNA-Trp; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.908 |
ffh | secY | A3E83_03045 | A3E83_03485 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.959 |
guaA | OGT46538.1 | A3E83_03000 | A3E83_01370 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Protein TolA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.763 |