OGY63353.1 protein (Harrisonbacteria bacterium RIFCSPHIGHO202FULL4216)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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Experiments

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[Homology]

Score

OGY63353.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)

Predicted Functional Partners:

OGY63352.1

0.856

OGY63458.1

0.618

OGY63350.1

0.548

OGY63351.1

0.548

OGY63354.1

0.406

Your Current Organism:

Harrisonbacteria bacterium RIFCSPHIGHO202FULL4216

NCBI taxonomy Id: 1798404
Other names: C. Harrisonbacteria bacterium RIFCSPHIGHO2_02_FULL_42_16, Candidatus Harrisonbacteria bacterium RIFCSPHIGHO2_02_FULL_42_16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OGY63350.1	OGY63351.1	A3B92_01940	A3B92_01945	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.917
OGY63350.1	OGY63352.1	A3B92_01940	A3B92_01950	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.551
OGY63350.1	OGY63353.1	A3B92_01940	A3B92_01955	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.548
OGY63351.1	OGY63350.1	A3B92_01945	A3B92_01940	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.917
OGY63351.1	OGY63352.1	A3B92_01945	A3B92_01950	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.571
OGY63351.1	OGY63353.1	A3B92_01945	A3B92_01955	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.548
OGY63352.1	OGY63350.1	A3B92_01950	A3B92_01940	NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.551
OGY63352.1	OGY63351.1	A3B92_01950	A3B92_01945	NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.571
OGY63352.1	OGY63353.1	A3B92_01950	A3B92_01955	NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.856
OGY63352.1	OGY63354.1	A3B92_01950	A3B92_01960	NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.406
OGY63352.1	OGY63458.1	A3B92_01950	A3B92_01565	NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Superoxide dismutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.513
OGY63353.1	OGY63350.1	A3B92_01955	A3B92_01940	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.548
OGY63353.1	OGY63351.1	A3B92_01955	A3B92_01945	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.548
OGY63353.1	OGY63352.1	A3B92_01955	A3B92_01950	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.856
OGY63353.1	OGY63354.1	A3B92_01955	A3B92_01960	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.406
OGY63353.1	OGY63458.1	A3B92_01955	A3B92_01565	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Superoxide dismutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.618
OGY63354.1	OGY63352.1	A3B92_01960	A3B92_01950	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.406
OGY63354.1	OGY63353.1	A3B92_01960	A3B92_01955	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.406
OGY63458.1	OGY63352.1	A3B92_01565	A3B92_01950	Superoxide dismutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.513
OGY63458.1	OGY63353.1	A3B92_01565	A3B92_01955	Superoxide dismutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.618

Network Stats

number of nodes:

11

number of edges:

22

average node degree:

4

avg. local clustering coefficient:

0.855

expected number of edges:

11

PPI enrichment p-value:

0.00371

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030527

Structural constituent of chromatin

2 of 2

2.67

1.16

0.0077

GO:0005198

Structural molecule activity

4 of 56

1.52

1.12

0.0032

GO:0003676

Nucleic acid binding

7 of 522

0.8

0.56

0.0077

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0043232

Intracellular non-membrane-bounded organelle

4 of 97

1.28

0.92

0.0052

GO:0005694

Chromosome

2 of 29

1.51

0.66

0.0463

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2589

Mixed, incl. Histone-like DNA-binding protein, and Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily

4 of 5

2.57

3.08

1.61e-06

CL:8089

Antiport

2 of 5

2.27

0.81

0.0326

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0050

Antiport

2 of 4

2.37

1.03

0.0129

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00999

Sodium/hydrogen exchanger family

2 of 4

2.37

0.77

0.0397

PF02254

TrkA-N domain

2 of 6

2.19

0.76

0.0397

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR010992

Integration host factor (IHF)-like DNA-binding domain superfamily

2 of 2

2.67

0.78

0.0384

IPR000119

Histone-like DNA-binding protein

2 of 2

2.67

0.78

0.0384

IPR006153

Cation/H+ exchanger

2 of 4

2.37

0.77

0.0384

IPR003148

Regulator of K+ conductance, N-terminal

2 of 6

2.19

0.73

0.0446

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00411

Bacterial (prokaryotic) histone like domain

2 of 2

2.67

1.37

0.0032

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