STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OGY89957.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (412 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.861
OGY89286.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the dihydrofolate reductase family.
     
 0.826
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
 0.826
A2927_01170
Hypothetical protein; Too many ambiguous residues; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
  0.772
A2927_02060
Hypothetical protein; Too many ambiguous residues; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.771
nusB
Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. Belongs to the NusB family.
  
 
 0.685
hppA
Sodium-translocating pyrophosphatase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
    0.587
OGY89958.1
DNA protecting protein DprA; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
    0.582
ileS
Hypothetical protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
   0.531
A2927_01125
Restriction endonuclease subunit M; Incomplete; too short partial abutting assembly gap; missing stop; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the Nudix hydrolase family.
  
 
 0.500
Your Current Organism:
Komeilibacteria bacterium RIFCSPLOWO201FULL4510
NCBI taxonomy Id: 1798550
Other names: C. Komeilibacteria bacterium RIFCSPLOWO2_01_FULL_45_10, Candidatus Komeilibacteria bacterium RIFCSPLOWO2_01_FULL_45_10
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