STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OGG87301.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (241 aa)    
Predicted Functional Partners:
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.792
A3B87_03700
Hypothetical protein; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.743
A3B87_00990
Hypothetical protein; Catalyzes the reversible phosphorylation of UMP to UDP.
    
  0.731
OGG87195.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
  0.728
adk
Hypothetical protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
  0.725
OGG86645.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
     
 0.690
OGG87302.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.595
OGG87303.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.578
OGG87319.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
  0.574
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.481
Your Current Organism:
Kuenenbacteria bacterium RIFCSPHIGHO202FULL3913
NCBI taxonomy Id: 1798561
Other names: C. Kuenenbacteria bacterium RIFCSPHIGHO2_02_FULL_39_13, Candidatus Kuenenbacteria bacterium RIFCSPHIGHO2_02_FULL_39_13
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