STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppnKNAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (299 aa)    
Predicted Functional Partners:
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.825
OGV30430.1
DNA repair protein RecN; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
  
 0.815
OGV30207.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.790
OGV28560.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.634
OGV28921.1
NADP-dependent isocitrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.620
surE
5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.616
A3E88_08180
Molecular chaperone HtpG; Frameshifted; too many ambiguous residues; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.608
OGV28929.1
Succinate-semialdehyde dehydrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.604
OGV32370.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
  0.581
OGV30213.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
  0.580
Your Current Organism:
Legionellales bacterium RIFCSPHIGHO212FULL3511
NCBI taxonomy Id: 1798567
Other names: L. bacterium RIFCSPHIGHO2_12_FULL_35_11, Legionellales bacterium RIFCSPHIGHO2_12_FULL_35_11
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