STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OGV18956.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (436 aa)    
Predicted Functional Partners:
OGV17362.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.880
OGV17363.1
Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.773
OGV21653.1
3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LeuD family.
  
  
 0.680
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.576
OGV17513.1
Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.568
OGV17179.1
Aminodeoxychorismate synthase, component I; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.557
OGV20630.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.556
OGV21114.1
Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.542
OGV17423.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.536
OGV20162.1
Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.534
Your Current Organism:
Lentisphaerae bacterium GWF23869
NCBI taxonomy Id: 1798570
Other names: L. bacterium GWF2_38_69, Lentisphaerae bacterium GWF2_38_69
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.