STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OJF92694.1Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)    
Predicted Functional Partners:
lysS
lysine--tRNA ligase; Class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.937
OJF99986.1
methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.900
OJG00233.1
proline--tRNA ligase; Catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.899
OJG01421.1
glutamate--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.892
OJF92311.1
glutamyl-Q tRNA(Asp) synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.892
OJF97913.1
DNA-directed RNA polymerase subunit alpha; Catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.869
OJF91350.1
leucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.868
OJF90044.1
arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.857
ileS
isoleucine--tRNA ligase; IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme; Derived by automated computational analysis using gene prediction [...]
   
 0.852
OJF97882.1
DNA-directed RNA polymerase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.831
Your Current Organism:
Pararhizobium antarcticum
NCBI taxonomy Id: 1798805
Other names: DSM 103442, LMG 29675, LMG:29675, P. antarcticum, Pararhizobium antarcticum Naqvi et al. 2017, Rhizobium sp. 59, strain NAQVI 59
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