STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (341 aa)    
Predicted Functional Partners:
kbl
Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
 
 0.997
KXI29572.1
Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.856
KXI30759.1
8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.834
KXI26731.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.772
KXI26749.1
Vanillate O-demethylase oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.772
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.763
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
 0.737
KXI30302.1
Threonine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.737
KXI28714.1
Rubredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.705
KXI27565.1
Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.687
Your Current Organism:
Paraglaciecola hydrolytica
NCBI taxonomy Id: 1799789
Other names: DSM 102834, LMG 29457, LMG:29457, NCIMB 15060, P. hydrolytica, Paraglaciecola hydrolytica Bech et al. 2017, Paraglaciecola sp. S66, strain S66
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