KXI29875.1 protein (Paraglaciecola hydrolytica)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

KXI29875.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (658 aa)

Predicted Functional Partners:

KXI26827.1

0.862

cpsB

0.750

KXI30526.1

0.737

KXI27595.1

0.554

KXI30324.1

0.554

KXI28487.1

0.554

KXI28528.1

0.554

KXI28144.1

0.554

KXI27225.1

0.554

KXI27229.1

0.554

Your Current Organism:

Paraglaciecola hydrolytica

NCBI taxonomy Id: 1799789
Other names: DSM 102834, LMG 29457, LMG:29457, NCIMB 15060, P. hydrolytica, Paraglaciecola hydrolytica Bech et al. 2017, Paraglaciecola sp. S66, strain S66

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KXI26827.1	KXI27225.1	AX660_03405	AX660_21060	Undecaprenyl-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.883
KXI26827.1	KXI27229.1	AX660_03405	AX660_21080	Undecaprenyl-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.957
KXI26827.1	KXI27595.1	AX660_03405	AX660_00885	Undecaprenyl-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.945
KXI26827.1	KXI28144.1	AX660_03405	AX660_17315	Undecaprenyl-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.883
KXI26827.1	KXI28487.1	AX660_03405	AX660_15455	Undecaprenyl-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.911
KXI26827.1	KXI28528.1	AX660_03405	AX660_15675	Undecaprenyl-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.883
KXI26827.1	KXI29875.1	AX660_03405	AX660_07560	Undecaprenyl-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.862
KXI26827.1	KXI30324.1	AX660_03405	AX660_10125	Undecaprenyl-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.883
KXI26827.1	cpsB	AX660_03405	AX660_04175	Undecaprenyl-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Mannose-1-phosphate guanyltransferase; Capsular polysaccharide colanic acid biosynthesis protein; catalyzes the formation of GDP-mannose from GTP and alpha-D-mannose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 2 family.	0.996
KXI27225.1	KXI26827.1	AX660_21060	AX660_03405	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Undecaprenyl-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.883
KXI27225.1	KXI29875.1	AX660_21060	AX660_07560	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.554
KXI27225.1	cpsB	AX660_21060	AX660_04175	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Mannose-1-phosphate guanyltransferase; Capsular polysaccharide colanic acid biosynthesis protein; catalyzes the formation of GDP-mannose from GTP and alpha-D-mannose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 2 family.	0.495
KXI27229.1	KXI26827.1	AX660_21080	AX660_03405	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Undecaprenyl-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.957
KXI27229.1	KXI29875.1	AX660_21080	AX660_07560	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.554
KXI27229.1	cpsB	AX660_21080	AX660_04175	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Mannose-1-phosphate guanyltransferase; Capsular polysaccharide colanic acid biosynthesis protein; catalyzes the formation of GDP-mannose from GTP and alpha-D-mannose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 2 family.	0.495
KXI27595.1	KXI26827.1	AX660_00885	AX660_03405	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Undecaprenyl-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.945
KXI27595.1	KXI28487.1	AX660_00885	AX660_15455	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.687
KXI27595.1	KXI29875.1	AX660_00885	AX660_07560	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.554
KXI27595.1	cpsB	AX660_00885	AX660_04175	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Mannose-1-phosphate guanyltransferase; Capsular polysaccharide colanic acid biosynthesis protein; catalyzes the formation of GDP-mannose from GTP and alpha-D-mannose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 2 family.	0.495
KXI28144.1	KXI26827.1	AX660_17315	AX660_03405	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Undecaprenyl-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.883

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

32

average node degree:

5.82

avg. local clustering coefficient:

0.667

expected number of edges:

11

PPI enrichment p-value:

2.07e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015031

Protein transport

10 of 110

1.56

3.15

2.22e-12

GO:0071705

Nitrogen compound transport

11 of 190

1.36

2.44

2.22e-12

GO:0071702

Organic substance transport

11 of 277

1.2

1.85

1.58e-11

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0022857

Transmembrane transporter activity

11 of 432

1.0

1.24

8.14e-09

GO:0031992

Energy transducer activity

2 of 4

2.3

0.9

0.0222

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005887

Integral component of plasma membrane

6 of 58

1.61

2.42

2.37e-07

GO:0005886

Plasma membrane

11 of 653

0.82

0.88

1.31e-07

GO:0016021

Integral component of membrane

11 of 967

0.65

0.62

1.90e-06

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5771

Mixed, incl. TonB, C-terminal, and MotA/TolQ/ExbB proton channel

8 of 20

2.2

5.9

3.02e-14

CL:5763

TonB-dependent receptor-like, beta-barrel domain superfamily, and Protein transport

10 of 63

1.8

4.52

9.53e-15

CL:5764

TonB-dependent receptor-like, beta-barrel domain superfamily, and Protein transport

9 of 56

1.8

4.32

1.32e-13

CL:5772

Mixed, incl. MotA/TolQ/ExbB proton channel, and Energy transducer activity

5 of 13

2.18

3.64

2.60e-08

CL:5786

Mixed, incl. Putative MotA/TolQ/ExbB family protein, and Energy transducer activity

3 of 6

2.3

2.14

8.01e-05

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005886

Plasma membrane

9 of 526

0.83

0.77

8.07e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0653

Protein transport

10 of 45

1.94

5.58

1.11e-16

KW-0735

Signal-anchor

2 of 5

2.2

1.23

0.0048

KW-0812

Transmembrane

11 of 949

0.66

0.62

4.44e-06

KW-0997

Cell inner membrane

3 of 81

1.17

0.61

0.0347

KW-1133

Transmembrane helix

10 of 904

0.64

0.56

6.65e-05

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01618

MotA/TolQ/ExbB proton channel family

8 of 11

2.46

6.99

2.48e-15

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR002898

MotA/TolQ/ExbB proton channel

8 of 11

2.46

6.82

6.37e-15

IPR017270

Putative MotA/TolQ/ExbB family protein

2 of 2

2.6

0.85

0.0288

IPR003538

Gram-negative bacterial TonB protein

2 of 4

2.3

0.72

0.0479

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