STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXI30530.1SprT family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SprT family. (144 aa)    
Predicted Functional Partners:
KXI28688.1
Transcriptional regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish d [...]
  
     0.725
KXI27484.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0352 family.
  
     0.662
KXI27485.1
Nucleoid-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.590
AX660_19040
Hypothetical protein; Too many ambiguous residues; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.553
AX660_07730
Signal peptide peptidase SppA; Too many ambiguous residues; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.529
KXI30033.1
Flavodoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.523
bamC
Outer membrane assembly protein BamC; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.512
zipA
Hypothetical protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
  
     0.475
rraB
Regulator; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.471
KXI27320.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.460
Your Current Organism:
Paraglaciecola hydrolytica
NCBI taxonomy Id: 1799789
Other names: DSM 102834, LMG 29457, LMG:29457, NCIMB 15060, P. hydrolytica, Paraglaciecola hydrolytica Bech et al. 2017, Paraglaciecola sp. S66, strain S66
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