KXI30434.1 protein (Paraglaciecola hydrolytica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

KXI30434.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (161 aa)

Predicted Functional Partners:

KXI30093.1

0.929

KXI28029.1

0.860

KXI29990.1

0.814

KXI30435.1

0.773

KXI30436.1

0.737

KXI27962.1

0.713

KXI28903.1

0.628

KXI29992.1

0.614

KXI30437.1

0.513

aroQ

0.511

Your Current Organism:

Paraglaciecola hydrolytica

NCBI taxonomy Id: 1799789
Other names: DSM 102834, LMG 29457, LMG:29457, NCIMB 15060, P. hydrolytica, Paraglaciecola hydrolytica Bech et al. 2017, Paraglaciecola sp. S66, strain S66

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KXI27962.1	KXI28903.1	AX660_20905	AX660_11980	Oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.764
KXI27962.1	KXI29990.1	AX660_20905	AX660_08245	Oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.899
KXI27962.1	KXI29992.1	AX660_20905	AX660_08255	Oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
KXI27962.1	KXI30093.1	AX660_20905	AX660_08830	Oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Carbamoyl-phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
KXI27962.1	KXI30434.1	AX660_20905	AX660_10745	Oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.713
KXI28029.1	KXI30434.1	AX660_20985	AX660_10745	Homogentisate 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.860
KXI28903.1	KXI27962.1	AX660_11980	AX660_20905	Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.764
KXI28903.1	KXI29992.1	AX660_11980	AX660_08255	Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.449
KXI28903.1	KXI30093.1	AX660_11980	AX660_08830	Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Carbamoyl-phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.820
KXI28903.1	KXI30434.1	AX660_11980	AX660_10745	Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.628
KXI29990.1	KXI27962.1	AX660_08245	AX660_20905	methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.899
KXI29990.1	KXI29992.1	AX660_08245	AX660_08255	methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
KXI29990.1	KXI30093.1	AX660_08245	AX660_08830	methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Carbamoyl-phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
KXI29990.1	KXI30434.1	AX660_08245	AX660_10745	methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.814
KXI29992.1	KXI27962.1	AX660_08255	AX660_20905	3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
KXI29992.1	KXI28903.1	AX660_08255	AX660_11980	3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.449
KXI29992.1	KXI29990.1	AX660_08255	AX660_08245	3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
KXI29992.1	KXI30093.1	AX660_08255	AX660_08830	3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Carbamoyl-phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
KXI29992.1	KXI30434.1	AX660_08255	AX660_10745	3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.614
KXI30093.1	KXI27962.1	AX660_08830	AX660_20905	Carbamoyl-phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	Oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999

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Network Stats

number of nodes:

11

number of edges:

47

average node degree:

8.55

avg. local clustering coefficient:

0.894

expected number of edges:

11

PPI enrichment p-value:

2.22e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0090151

Establishment of protein localization to mitochondrial membrane

5 of 33

2.09

3.04

4.29e-07

GO:0072655

Establishment of protein localization to mitochondrion

6 of 58

1.92

2.99

1.71e-07

GO:0006839

Mitochondrial transport

6 of 59

1.92

2.97

1.71e-07

GO:0051205

Protein insertion into membrane

5 of 45

1.95

2.72

1.20e-06

GO:0006626

Protein targeting to mitochondrion

5 of 49

1.92

2.64

1.53e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030943

Mitochondrion targeting sequence binding

2 of 4

2.61

0.83

0.0307

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0032592

Integral component of mitochondrial membrane

6 of 48

2.0

3.49

1.42e-08

GO:0005741

Mitochondrial outer membrane

6 of 54

1.95

3.41

1.42e-08

GO:0031307

Integral component of mitochondrial outer membrane

4 of 14

2.36

3.21

5.35e-07

GO:0031966

Mitochondrial membrane

7 of 306

1.27

1.6

1.52e-06

GO:0000127

Transcription factor TFIIIC complex

2 of 4

2.61

1.59

0.0012

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9394

Protein localization to mitochondrion, and Mitochondrial calcium ion transport

5 of 41

1.99

2.66

2.14e-06

CL:9397

Protein import into mitochondrial matrix, and Tim10-like

3 of 22

2.04

1.57

0.00085

CL:9426

Mitochondrial outer membrane translocase complex

2 of 5

2.51

1.19

0.0067

CL:1471

Transcription factor TFIIIC complex

2 of 5

2.51

1.19

0.0067

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031307

Integral component of mitochondrial outer membrane

4 of 11

2.47

3.41

2.79e-07

GOCC:0032592

Integral component of mitochondrial membrane

5 of 33

2.09

3.18

1.90e-07

GOCC:0005741

Mitochondrial outer membrane

6 of 74

1.82

2.81

1.90e-07

GOCC:0031966

Mitochondrial membrane

7 of 241

1.37

1.88

4.38e-07

GOCC:0005742

Mitochondrial outer membrane translocase complex

2 of 5

2.51

1.53

0.0015

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