AZE42_12985 protein (Rhizopogon vesiculosus)

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query proteins and first shell of interactors

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

AZE42_12985

Uncharacterized protein. (128 aa)

Predicted Functional Partners:

AZE42_08601

0.584

AZE42_11381

0.572

AZE42_02639

0.572

AZE42_05863

0.545

AZE42_05515

0.521

AZE42_04834

0.518

AZE42_04833

0.518

AZE42_06769

0.510

AZE42_06184

0.510

AZE42_06853

0.503

Your Current Organism:

Rhizopogon vesiculosus

NCBI taxonomy Id: 180088
Other names: R. vesiculosus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AZE42_02639	AZE42_04833	A0A1J8QR41	A0A1J8PJ78	Uncharacterized protein.	Uncharacterized protein.	0.456
AZE42_02639	AZE42_04834	A0A1J8QR41	A0A1J8PHB4	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.456
AZE42_02639	AZE42_05863	A0A1J8QR41	A0A1J8R2Z0	Uncharacterized protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.976
AZE42_02639	AZE42_06853	A0A1J8QR41	A0A1J8QJX0	Uncharacterized protein.	V-SNARE coiled-coil homology domain-containing protein.	0.768
AZE42_02639	AZE42_08601	A0A1J8QR41	A0A1J8QD61	Uncharacterized protein.	USP domain-containing protein; Belongs to the peptidase C19 family.	0.511
AZE42_02639	AZE42_12985	A0A1J8QR41	A0A1J8PHX8	Uncharacterized protein.	Uncharacterized protein.	0.572
AZE42_04833	AZE42_02639	A0A1J8PJ78	A0A1J8QR41	Uncharacterized protein.	Uncharacterized protein.	0.456
AZE42_04833	AZE42_11381	A0A1J8PJ78	A0A1J8QJL0	Uncharacterized protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.456
AZE42_04833	AZE42_12985	A0A1J8PJ78	A0A1J8PHX8	Uncharacterized protein.	Uncharacterized protein.	0.518
AZE42_04834	AZE42_02639	A0A1J8PHB4	A0A1J8QR41	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein.	0.456
AZE42_04834	AZE42_11381	A0A1J8PHB4	A0A1J8QJL0	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.456
AZE42_04834	AZE42_12985	A0A1J8PHB4	A0A1J8PHX8	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein.	0.518
AZE42_05515	AZE42_06853	A0A1J8Q9C5	A0A1J8QJX0	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	V-SNARE coiled-coil homology domain-containing protein.	0.670
AZE42_05515	AZE42_12985	A0A1J8Q9C5	A0A1J8PHX8	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Uncharacterized protein.	0.521
AZE42_05863	AZE42_02639	A0A1J8R2Z0	A0A1J8QR41	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.976
AZE42_05863	AZE42_11381	A0A1J8R2Z0	A0A1J8QJL0	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.989
AZE42_05863	AZE42_12985	A0A1J8R2Z0	A0A1J8PHX8	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.545
AZE42_06184	AZE42_12985	A0A1J8R2U6	A0A1J8PHX8	ABC transporter domain-containing protein.	Uncharacterized protein.	0.510
AZE42_06769	AZE42_12985	A0A1J8QC27	A0A1J8PHX8	Uncharacterized protein.	Uncharacterized protein.	0.510
AZE42_06853	AZE42_02639	A0A1J8QJX0	A0A1J8QR41	V-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.768

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

41

average node degree:

7.45

avg. local clustering coefficient:

0.924

expected number of edges:

14

PPI enrichment p-value:

4.8e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 188

1.3

2.17

1.56e-11

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

11 of 85

1.65

3.94

1.42e-15

GO:0019843

rRNA binding

3 of 28

1.56

0.8

0.0228

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 96

1.59

3.65

3.29e-15

GO:0044391

Ribosomal subunit

6 of 71

1.46

1.88

3.62e-06

GO:0015934

Large ribosomal subunit

4 of 40

1.53

1.38

0.00057

GO:0005761

Mitochondrial ribosome

3 of 26

1.6

1.07

0.0053

GO:0005762

Mitochondrial large ribosomal subunit

2 of 13

1.72

0.71

0.0410

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2525

Structural constituent of ribosome

10 of 16

2.33

8.2

1.05e-19

CL:2522

Organellar ribosome, and SRP-dependent cotranslational protein targeting to membrane

11 of 34

2.04

6.77

1.05e-19

CL:2527

Mixed, incl. L28p-like, and Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like

5 of 5

2.53

4.62

1.01e-09

CL:2541

SRP-dependent cotranslational protein targeting to membrane

4 of 8

2.23

3.01

9.67e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

11 of 93

1.61

3.81

5.20e-16

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72766

Translation

10 of 157

1.34

2.2

1.75e-10

MAP-72706

GTP hydrolysis and joining of the 60S ribosomal subunit

6 of 62

1.52

1.95

4.37e-06

MAP-72689

Formation of a pool of free 40S subunits

6 of 65

1.5

1.92

4.37e-06

MAP-975956

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

6 of 67

1.49

1.9

4.37e-06

MAP-1799339

SRP-dependent cotranslational protein targeting to membrane

6 of 67

1.49

1.9

4.37e-06

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0044391

Ribosomal subunit

7 of 74

1.51

2.19

3.06e-07

GOCC:0022626

Cytosolic ribosome

5 of 54

1.5

1.68

4.13e-05

GOCC:0015934

Large ribosomal subunit

4 of 43

1.5

1.37

0.00050

GOCC:0015935

Small ribosomal subunit

3 of 30

1.53

1.03

0.0058

GOCC:0022625

Cytosolic large ribosomal subunit

3 of 31

1.52

1.02

0.0058

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

5 of 63

1.43

1.48

0.00012

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