node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AZE42_00139 | AZE42_02662 | A0A1J8Q3S5 | A0A1J8PZC7 | Cytochrome b5 heme-binding domain-containing protein. | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | 0.780 |
AZE42_00139 | AZE42_03532 | A0A1J8Q3S5 | A0A1J8PZ37 | Cytochrome b5 heme-binding domain-containing protein. | S5A_REDUCTASE domain-containing protein. | 0.810 |
AZE42_00139 | AZE42_03802 | A0A1J8Q3S5 | A0A1J8QSL5 | Cytochrome b5 heme-binding domain-containing protein. | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | 0.797 |
AZE42_00139 | AZE42_06258 | A0A1J8Q3S5 | A0A1J8PMW7 | Cytochrome b5 heme-binding domain-containing protein. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.500 |
AZE42_00139 | AZE42_07494 | A0A1J8Q3S5 | A0A1J8QFE0 | Cytochrome b5 heme-binding domain-containing protein. | Elongation of fatty acids protein. | 0.767 |
AZE42_00139 | AZE42_08628 | A0A1J8Q3S5 | A0A1J8QAI9 | Cytochrome b5 heme-binding domain-containing protein. | Cytochrome b5 heme-binding domain-containing protein. | 0.797 |
AZE42_00139 | AZE42_10219 | A0A1J8Q3S5 | A0A1J8QMK1 | Cytochrome b5 heme-binding domain-containing protein. | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | 0.797 |
AZE42_00142 | AZE42_03802 | A0A1J8R3B7 | A0A1J8QSL5 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | 0.442 |
AZE42_00142 | AZE42_07494 | A0A1J8R3B7 | A0A1J8QFE0 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Elongation of fatty acids protein. | 0.671 |
AZE42_00142 | AZE42_08628 | A0A1J8R3B7 | A0A1J8QAI9 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Cytochrome b5 heme-binding domain-containing protein. | 0.442 |
AZE42_00142 | AZE42_10219 | A0A1J8R3B7 | A0A1J8QMK1 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | 0.442 |
AZE42_02662 | AZE42_00139 | A0A1J8PZC7 | A0A1J8Q3S5 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | Cytochrome b5 heme-binding domain-containing protein. | 0.780 |
AZE42_02662 | AZE42_03532 | A0A1J8PZC7 | A0A1J8PZ37 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | S5A_REDUCTASE domain-containing protein. | 0.986 |
AZE42_02662 | AZE42_03802 | A0A1J8PZC7 | A0A1J8QSL5 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | 0.946 |
AZE42_02662 | AZE42_06258 | A0A1J8PZC7 | A0A1J8PMW7 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.930 |
AZE42_02662 | AZE42_07494 | A0A1J8PZC7 | A0A1J8QFE0 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | Elongation of fatty acids protein. | 0.822 |
AZE42_02662 | AZE42_08628 | A0A1J8PZC7 | A0A1J8QAI9 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | Cytochrome b5 heme-binding domain-containing protein. | 0.875 |
AZE42_02662 | AZE42_10219 | A0A1J8PZC7 | A0A1J8QMK1 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | 0.875 |
AZE42_03532 | AZE42_00139 | A0A1J8PZ37 | A0A1J8Q3S5 | S5A_REDUCTASE domain-containing protein. | Cytochrome b5 heme-binding domain-containing protein. | 0.810 |
AZE42_03532 | AZE42_02662 | A0A1J8PZ37 | A0A1J8PZC7 | S5A_REDUCTASE domain-containing protein. | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | 0.986 |