AZE42_03148 protein (Rhizopogon vesiculosus)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:

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Gene Fusion

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Coexpression

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[Homology]

Score

AZE42_03148

tRNA (guanine(26)-N(2))-dimethyltransferase. (573 aa)

Predicted Functional Partners:

AZE42_02519

0.830

AZE42_00802

0.817

AZE42_06400

0.788

AZE42_07991

0.777

AZE42_02542

0.737

TRM8

0.735

AZE42_07439

0.733

AZE42_09813

0.729

AZE42_05845

0.723

AZE42_02144

0.722

Your Current Organism:

Rhizopogon vesiculosus

NCBI taxonomy Id: 180088
Other names: R. vesiculosus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AZE42_00802	AZE42_02144	A0A1J8Q009	A0A1J8RBL4	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Uncharacterized protein.	0.573
AZE42_00802	AZE42_02519	A0A1J8Q009	A0A1J8QHU1	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	WD_REPEATS_REGION domain-containing protein.	0.868
AZE42_00802	AZE42_02542	A0A1J8Q009	A0A1J8R6L8	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	WD_REPEATS_REGION domain-containing protein.	0.836
AZE42_00802	AZE42_03148	A0A1J8Q009	A0A1J8QFN7	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	tRNA (guanine(26)-N(2))-dimethyltransferase.	0.817
AZE42_00802	AZE42_05845	A0A1J8Q009	A0A1J8Q2Z2	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	WD_REPEATS_REGION domain-containing protein.	0.903
AZE42_00802	AZE42_06400	A0A1J8Q009	A0A1J8PT94	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.868
AZE42_00802	AZE42_07439	A0A1J8Q009	A0A1J8PUU3	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	TruB_N domain-containing protein.	0.757
AZE42_00802	AZE42_07991	A0A1J8Q009	A0A1J8QKP5	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Brix domain-containing protein.	0.992
AZE42_00802	AZE42_09813	A0A1J8Q009	A0A1J8Q3R2	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Uncharacterized protein.	0.429
AZE42_00802	TRM8	A0A1J8Q009	A0A1J8Q2Q4	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.	0.785
AZE42_02144	AZE42_00802	A0A1J8RBL4	A0A1J8Q009	Uncharacterized protein.	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.573
AZE42_02144	AZE42_02519	A0A1J8RBL4	A0A1J8QHU1	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.719
AZE42_02144	AZE42_02542	A0A1J8RBL4	A0A1J8R6L8	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.513
AZE42_02144	AZE42_03148	A0A1J8RBL4	A0A1J8QFN7	Uncharacterized protein.	tRNA (guanine(26)-N(2))-dimethyltransferase.	0.722
AZE42_02144	AZE42_05845	A0A1J8RBL4	A0A1J8Q2Z2	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.504
AZE42_02144	AZE42_06400	A0A1J8RBL4	A0A1J8PT94	Uncharacterized protein.	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.675
AZE42_02144	AZE42_07439	A0A1J8RBL4	A0A1J8PUU3	Uncharacterized protein.	TruB_N domain-containing protein.	0.651
AZE42_02144	AZE42_07991	A0A1J8RBL4	A0A1J8QKP5	Uncharacterized protein.	Brix domain-containing protein.	0.772
AZE42_02144	AZE42_09813	A0A1J8RBL4	A0A1J8Q3R2	Uncharacterized protein.	Uncharacterized protein.	0.424
AZE42_02144	TRM8	A0A1J8RBL4	A0A1J8Q2Q4	Uncharacterized protein.	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.	0.819

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Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0033184

Positive regulation of histone ubiquitination

3 of 3

3.98

3.94

8.49e-08

GO:0009788

Negative regulation of abscisic acid-activated signaling pathway

3 of 87

2.52

2.3

5.00e-05

GO:0045324

Late endosome to vacuole transport

3 of 138

2.32

2.04

0.00013

GO:0016197

Endosomal transport

3 of 227

2.1

1.73

0.00042

GO:0032940

Secretion by cell

3 of 311

1.96

1.55

0.00082

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004197

Cysteine-type endopeptidase activity

6 of 438

2.12

3.78

6.84e-09

GO:0043621

Protein self-association

3 of 640

1.65

0.88

0.0166

GO:0140096

Catalytic activity, acting on a protein

10 of 12949

0.87

7.24e-06

GO:0004842

Ubiquitin-protein transferase activity

4 of 2092

1.26

0.74

0.0182

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005764

Lysosome

6 of 339

2.23

4.4

5.03e-10

GO:0005615

Extracellular space

6 of 730

1.89

3.28

1.59e-08

GO:0005769

Early endosome

3 of 105

2.44

2.38

3.19e-05

GO:0005802

trans-Golgi network

3 of 598

1.68

1.18

0.0034

GO:0000325

Plant-type vacuole

3 of 1274

1.35

0.75

0.0211

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:155551

Granulin, and YggU-like superfamily

7 of 20

3.52

10.3

1.61e-19

CL:155556

Granulin, and YggU-like superfamily

6 of 15

3.58

9.17

2.17e-17

CL:155561

Granulin, and YggU-like superfamily

4 of 10

3.58

5.63

6.67e-11

CL:29896

Mind bomb, SH3 repeat domain, and Extension to Ser/Thr-type protein kinases

3 of 11

3.42

3.61

2.99e-07

CL:155566

YggU-like superfamily, and Granulin

2 of 5

3.58

2.2

0.00011

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04145

Phagosome

6 of 495

2.06

4.04

8.11e-10

map04144

Endocytosis

3 of 1052

1.44

0.87

0.0123

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-6798695

Neutrophil degranulation

6 of 5151

1.05

0.77

0.0046

MAP-168249

Innate Immune System

6 of 6470

0.95

0.66

0.0078

MAP-168256

Immune System

7 of 10100

0.82

0.58

0.0078

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005769

Early endosome

3 of 114

2.4

1.99

0.00018

GOCC:0110165

Cellular anatomical entity

10 of 8339

1.06

1.29

1.70e-07

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0788

Thiol protease

5 of 199

2.38

4.19

4.28e-09

KW-0040

ANK repeat

3 of 502

1.76

1.31

0.0019

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00069

Protein kinase domain

3 of 474

1.78

0.68

0.0488

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR037277

Granulin superfamily

5 of 21

3.36

6.56

1.12e-12

IPR000118

Granulin

5 of 21

3.36

6.56

1.12e-12

IPR039417

Papain-like cysteine endopeptidase

7 of 240

2.44

5.85

1.12e-12

IPR013128

Peptidase C1A

7 of 259

2.41

5.79

1.12e-12

IPR000668

Peptidase C1A, papain C-terminal

7 of 262

2.41

5.78

1.12e-12

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00277

Granulin

5 of 21

3.36

7.13

9.56e-14

SM00645

Papain family cysteine protease

7 of 247

2.43

6.28

9.56e-14

SM00848

Cathepsin propeptide inhibitor domain (I29)

5 of 247

2.29

3.98

7.64e-09

SM00248

Ankyrin repeats

3 of 525

1.74

1.21

0.0033

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