AZE42_02490 protein (Rhizopogon vesiculosus)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

AZE42_02490

BAR domain-containing protein. (294 aa)

Predicted Functional Partners:

AZE42_05918

0.973

AZE42_06478

0.972

AZE42_01484

0.891

AZE42_12645

0.891

AZE42_03814

0.876

AZE42_08479

0.855

AZE42_02363

0.855

AZE42_01805

0.855

AZE42_02512

0.832

AZE42_02143

0.761

Your Current Organism:

Rhizopogon vesiculosus

NCBI taxonomy Id: 180088
Other names: R. vesiculosus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AZE42_01484	AZE42_01805	A0A1J8PKS3	A0A1J8R7A6	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.878
AZE42_01484	AZE42_02363	A0A1J8PKS3	A0A1J8PRL0	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.876
AZE42_01484	AZE42_02490	A0A1J8PKS3	A0A1J8QHF6	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	BAR domain-containing protein.	0.891
AZE42_01484	AZE42_02512	A0A1J8PKS3	A0A1J8RAD0	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Uncharacterized protein.	0.776
AZE42_01484	AZE42_03814	A0A1J8PKS3	A0A1J8R3U8	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Uncharacterized protein.	0.837
AZE42_01484	AZE42_06478	A0A1J8PKS3	A0A1J8PT70	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Uncharacterized protein.	0.732
AZE42_01484	AZE42_08479	A0A1J8PKS3	A0A1J8PNI6	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.876
AZE42_01805	AZE42_01484	A0A1J8R7A6	A0A1J8PKS3	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.878
AZE42_01805	AZE42_02363	A0A1J8R7A6	A0A1J8PRL0	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.601
AZE42_01805	AZE42_02490	A0A1J8R7A6	A0A1J8QHF6	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	BAR domain-containing protein.	0.855
AZE42_01805	AZE42_03814	A0A1J8R7A6	A0A1J8R3U8	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.730
AZE42_01805	AZE42_06478	A0A1J8R7A6	A0A1J8PT70	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.747
AZE42_01805	AZE42_08479	A0A1J8R7A6	A0A1J8PNI6	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.558
AZE42_01805	AZE42_12645	A0A1J8R7A6	A0A1J8PZB7	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	ENTH domain-containing protein.	0.878
AZE42_02143	AZE42_02490	A0A1J8QEP6	A0A1J8QHF6	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	BAR domain-containing protein.	0.761
AZE42_02143	AZE42_02512	A0A1J8QEP6	A0A1J8RAD0	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Uncharacterized protein.	0.761
AZE42_02143	AZE42_03814	A0A1J8QEP6	A0A1J8R3U8	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Uncharacterized protein.	0.982
AZE42_02143	AZE42_06478	A0A1J8QEP6	A0A1J8PT70	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Uncharacterized protein.	0.882
AZE42_02363	AZE42_01484	A0A1J8PRL0	A0A1J8PKS3	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.876
AZE42_02363	AZE42_01805	A0A1J8PRL0	A0A1J8R7A6	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.601

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Network Stats

number of nodes:

11

number of edges:

45

average node degree:

8.18

avg. local clustering coefficient:

0.879

expected number of edges:

10

PPI enrichment p-value:

5.55e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045721

Negative regulation of gluconeogenesis

6 of 7

3.04

7.23

3.43e-14

GO:0043161

Proteasome-mediated ubiquitin-dependent protein catabolic process

10 of 144

1.95

5.44

6.43e-16

GO:0007039

Protein catabolic process in the vacuole

2 of 3

2.93

1.81

0.00053

GO:0072666

Establishment of protein localization to vacuole

2 of 31

1.92

0.87

0.0214

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0034657

GID complex

9 of 11

3.02

11.46

1.16e-22

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:18129

GID complex, and CRA domain

10 of 15

2.93

12.54

2.66e-25

CL:18126

Mixed, incl. GID complex, and Yip1 domain

11 of 28

2.7

12.22

2.90e-26

CL:18132

Negative regulation of gluconeogenesis, and Regulation of endocytosis

6 of 10

2.89

6.82

1.30e-13

CL:18136

Negative regulation of gluconeogenesis

4 of 5

3.01

4.4

8.09e-09

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-3214815

HDACs deacetylate histones

5 of 12

2.73

4.89

5.64e-10

MAP-4839726

Chromatin organization

5 of 82

1.89

2.6

1.64e-06

MAP-3247509

Chromatin modifying enzymes

5 of 82

1.89

2.6

1.64e-06

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0034657

GID complex

8 of 10

3.01

9.88

1.73e-19

GOCC:0032991

Protein-containing complex

11 of 2626

0.73

0.7

4.45e-06

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0853

WD repeat

4 of 255

1.3

0.89

0.0071

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR006595

CTLH, C-terminal LisH motif

4 of 5

3.01

3.91

6.82e-08

IPR024964

CTLH/CRA C-terminal to LisH motif domain

3 of 5

2.89

2.5

2.68e-05

IPR006594

LIS1 homology motif

3 of 9

2.63

2.25

7.00e-05

IPR045098

Fyv10 family

2 of 2

3.11

1.46

0.0023

IPR044063

Gid-type RING finger domain

2 of 2

3.11

1.46

0.0023

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00668

C-terminal to LisH motif.

3 of 4

2.98

2.97

3.84e-06

SM00667

Lissencephaly type-1-like homology motif

3 of 9

2.63

2.65

1.20e-05

SM00757

CT11-RanBPM

2 of 4

2.81

1.68

0.00086

SM00320

WD40 repeats

4 of 272

1.28

0.97

0.0033

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