node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OJZ62713.1 | OJZ62714.1 | BRW64_25570 | BRW64_25575 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.590 |
OJZ62713.1 | OJZ66858.1 | BRW64_25570 | BRW64_06220 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutathione-dependent formaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.595 |
OJZ62713.1 | OJZ66859.1 | BRW64_25570 | BRW64_06225 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.651 |
OJZ62713.1 | OJZ67000.1 | BRW64_25570 | BRW64_07065 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.447 |
OJZ62713.1 | egtA | BRW64_25570 | BRW64_25545 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ergothioneine biosynthesis glutamate--cysteine ligase EgtA; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | 0.543 |
OJZ62713.1 | egtB | BRW64_25570 | BRW64_25550 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | iron(II)-dependent oxidoreductase EgtB; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.543 |
OJZ62713.1 | egtC | BRW64_25570 | BRW64_25555 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ergothioneine biosynthesis protein EgtC; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | 0.543 |
OJZ62713.1 | egtD | BRW64_25570 | BRW64_25560 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dimethylhistidine N-methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.543 |
OJZ62713.1 | egtE | BRW64_25570 | BRW64_25565 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ergothioneine biosynthesis PLP-dependent enzyme EgtE; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | 0.543 |
OJZ62714.1 | OJZ62713.1 | BRW64_25575 | BRW64_25570 | acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.590 |
OJZ62714.1 | egtA | BRW64_25575 | BRW64_25545 | acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ergothioneine biosynthesis glutamate--cysteine ligase EgtA; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | 0.426 |
OJZ62714.1 | egtB | BRW64_25575 | BRW64_25550 | acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | iron(II)-dependent oxidoreductase EgtB; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.426 |
OJZ62714.1 | egtC | BRW64_25575 | BRW64_25555 | acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ergothioneine biosynthesis protein EgtC; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | 0.426 |
OJZ62714.1 | egtD | BRW64_25575 | BRW64_25560 | acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dimethylhistidine N-methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.426 |
OJZ62714.1 | egtE | BRW64_25575 | BRW64_25565 | acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ergothioneine biosynthesis PLP-dependent enzyme EgtE; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | 0.426 |
OJZ66858.1 | OJZ62713.1 | BRW64_06220 | BRW64_25570 | Glutathione-dependent formaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.595 |
OJZ66858.1 | OJZ66859.1 | BRW64_06220 | BRW64_06225 | Glutathione-dependent formaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.922 |
OJZ66859.1 | OJZ62713.1 | BRW64_06225 | BRW64_25570 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.651 |
OJZ66859.1 | OJZ66858.1 | BRW64_06225 | BRW64_06220 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutathione-dependent formaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.922 |
OJZ67000.1 | OJZ62713.1 | BRW64_07065 | BRW64_25570 | LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.447 |