OGW10163.1 protein (Nitrospinae bacterium RIFCSPLOWO2123915)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

OGW10163.1

Glutamate-5-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)

Predicted Functional Partners:

OGW10162.1

0.999

OGW09360.1

0.876

OGW10164.1

0.854

OGW07432.1

0.813

OGW10165.1

0.806

OGW10760.1

0.795

OGW10161.1

0.743

OGW10726.1

0.695

OGW11366.1

0.687

OGW08172.1

0.672

Your Current Organism:

Nitrospinae bacterium RIFCSPLOWO2123915

NCBI taxonomy Id: 1801689
Other names: N. bacterium RIFCSPLOWO2_12_39_15, Nitrospinae bacterium RIFCSPLOWO2_12_39_15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OGW07432.1	OGW08172.1	A2W75_06810	A2W75_03755	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.598
OGW07432.1	OGW09360.1	A2W75_06810	A2W75_05735	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	F0F1 ATP synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.545
OGW07432.1	OGW10162.1	A2W75_06810	A2W75_00220	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate 5-kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.470
OGW07432.1	OGW10163.1	A2W75_06810	A2W75_00225	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate-5-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.813
OGW07432.1	OGW10760.1	A2W75_06810	A2W75_04625	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.470
OGW07432.1	OGW11366.1	A2W75_06810	A2W75_09340	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.646
OGW08172.1	OGW07432.1	A2W75_03755	A2W75_06810	Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.598
OGW08172.1	OGW10163.1	A2W75_03755	A2W75_00225	Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate-5-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.672
OGW08172.1	OGW10726.1	A2W75_03755	A2W75_04325	Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.681
OGW08172.1	OGW10760.1	A2W75_03755	A2W75_04625	Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.734
OGW09360.1	OGW07432.1	A2W75_05735	A2W75_06810	F0F1 ATP synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.545
OGW09360.1	OGW10163.1	A2W75_05735	A2W75_00225	F0F1 ATP synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate-5-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.876
OGW09360.1	OGW10726.1	A2W75_05735	A2W75_04325	F0F1 ATP synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.625
OGW09360.1	OGW11366.1	A2W75_05735	A2W75_09340	F0F1 ATP synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.429
OGW10161.1	OGW10162.1	A2W75_00215	A2W75_00220	GTPase ObgE; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Glutamate 5-kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.761
OGW10161.1	OGW10163.1	A2W75_00215	A2W75_00225	GTPase ObgE; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Glutamate-5-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.743
OGW10161.1	OGW10164.1	A2W75_00215	A2W75_00230	GTPase ObgE; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Nicotinate (nicotinamide) nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.605
OGW10161.1	OGW10165.1	A2W75_00215	A2W75_00235	GTPase ObgE; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Ribosome silencing factor; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.986
OGW10162.1	OGW07432.1	A2W75_00220	A2W75_06810	Glutamate 5-kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.470
OGW10162.1	OGW10161.1	A2W75_00220	A2W75_00215	Glutamate 5-kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	GTPase ObgE; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.761

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Network Stats

number of nodes:

11

number of edges:

18

average node degree:

3.27

avg. local clustering coefficient:

0.84

expected number of edges:

14

PPI enrichment p-value:

0.171

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006457

Protein folding

7 of 12

2.23

4.91

2.61e-11

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051082

Unfolded protein binding

6 of 7

2.4

4.72

3.09e-10

GO:0140662

ATP-dependent protein folding chaperone

4 of 5

2.37

2.96

1.89e-06

GO:0005515

Protein binding

7 of 42

1.69

2.89

1.15e-08

GO:0140657

ATP-dependent activity

6 of 141

1.1

1.03

0.00026

GO:0017076

Purine nucleotide binding

9 of 395

0.83

0.78

3.69e-05

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1054

0.45

0.33

0.0113

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:407

Protein folding, and Clp protease

9 of 12

2.34

7.19

1.14e-16

CL:402

Mixed, incl. Chaperone, and Protein catabolic process

10 of 28

2.02

5.94

1.14e-16

CL:409

Stress response, and Clp protease

5 of 6

2.39

4.05

9.10e-09

CL:80

Mixed, incl. Translation, and Chaperone

11 of 189

1.23

1.98

7.27e-12

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0143

Chaperone

6 of 15

2.07

3.83

3.17e-09

KW-0346

Stress response

5 of 8

2.26

3.77

2.04e-08

KW-0677

Repeat

2 of 11

1.73

0.71

0.0414

KW-0963

Cytoplasm

6 of 232

0.88

0.67

0.0034

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