OGW59602.1 protein (Nitrospirae bacterium RBG166422)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

OGW59602.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (234 aa)

Predicted Functional Partners:

OGW61063.1

0.996

OGW61923.1

0.993

OGW62086.1

0.988

OGW62744.1

0.988

OGW61924.1

0.983

OGW60466.1

0.983

OGW61126.1

0.966

OGW59598.1

0.961

OGW62690.1

0.961

OGW59120.1

0.961

Your Current Organism:

Nitrospirae bacterium RBG166422

NCBI taxonomy Id: 1801708
Other names: N. bacterium RBG_16_64_22, Nitrospirae bacterium RBG_16_64_22

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OGW59120.1	OGW59598.1	A2V83_11560	A2V83_03350	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.988
OGW59120.1	OGW59602.1	A2V83_11560	A2V83_03370	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.961
OGW59120.1	OGW60466.1	A2V83_11560	A2V83_09155	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.999
OGW59120.1	OGW61063.1	A2V83_11560	A2V83_03720	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.984
OGW59120.1	OGW61126.1	A2V83_11560	A2V83_10505	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.919
OGW59120.1	OGW61923.1	A2V83_11560	A2V83_02210	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.999
OGW59120.1	OGW61924.1	A2V83_11560	A2V83_02215	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.999
OGW59120.1	OGW62086.1	A2V83_11560	A2V83_06775	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.998
OGW59120.1	OGW62690.1	A2V83_11560	A2V83_10400	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.986
OGW59120.1	OGW62744.1	A2V83_11560	A2V83_08810	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.998
OGW59598.1	OGW59120.1	A2V83_03350	A2V83_11560	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.988
OGW59598.1	OGW59602.1	A2V83_03350	A2V83_03370	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.961
OGW59598.1	OGW60466.1	A2V83_03350	A2V83_09155	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.999
OGW59598.1	OGW61063.1	A2V83_03350	A2V83_03720	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.985
OGW59598.1	OGW61126.1	A2V83_03350	A2V83_10505	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.918
OGW59598.1	OGW61923.1	A2V83_03350	A2V83_02210	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.999
OGW59598.1	OGW61924.1	A2V83_03350	A2V83_02215	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.999
OGW59598.1	OGW62086.1	A2V83_03350	A2V83_06775	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.998
OGW59598.1	OGW62690.1	A2V83_03350	A2V83_10400	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.986
OGW59598.1	OGW62744.1	A2V83_03350	A2V83_08810	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.998

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Network Stats

number of nodes:

11

number of edges:

51

average node degree:

9.27

avg. local clustering coefficient:

0.927

expected number of edges:

10

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0055085

Transmembrane transport

11 of 553

0.96

1.13

4.11e-08

GO:0008643

Carbohydrate transport

3 of 41

1.53

0.75

0.0278

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015144

Carbohydrate transmembrane transporter activity

3 of 20

1.84

0.99

0.0114

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

8 of 922

0.6

0.4

0.0173

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7220

Mixed, incl. Bacterial extracellular solute-binding protein, and glycerol-3-phosphate transmembrane transporter activity

11 of 37

2.14

7.5

1.63e-20

CL:7222

Mixed, incl. glycerol-3-phosphate transmembrane transporter activity, and ABC-type carbohydrate transporter activity

10 of 28

2.22

7.42

8.63e-19

CL:7262

MalK, OB fold domain, and ABC-type carbohydrate transporter activity

6 of 8

2.54

5.59

8.74e-12

CL:7223

Mixed, incl. glycerol-3-phosphate transmembrane transporter activity, and ABC-type carbohydrate transporter activity

4 of 20

1.97

2.28

1.65e-05

CL:7247

Mixed, incl. glycerol-3-phosphate transmembrane transport, and ABC-type carbohydrate transporter activity

3 of 8

2.24

1.99

0.00015

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02010

ABC transporters

11 of 326

1.19

1.85

1.17e-11

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0043190

ATP-binding cassette (ABC) transporter complex

7 of 68

1.68

2.86

1.21e-08

GOCC:0055052

ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

3 of 19

1.86

1.69

0.00032

GOCC:1902517

glycerol-3-phosphate-transporting ATPase complex

2 of 3

2.49

1.6

0.0011

GOCC:0005886

Plasma membrane

10 of 723

0.81

1.68e-06

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0813

Transport

9 of 279

1.17

1.56

6.24e-08

KW-1003

Cell membrane

7 of 329

0.99

0.94

0.00016

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00528

Binding-protein-dependent transport system inner membrane component

7 of 65

1.7

2.85

1.99e-08

PF13416

Bacterial extracellular solute-binding protein

3 of 15

1.97

1.35

0.0023

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000515

ABC transporter type 1, transmembrane domain MetI-like

7 of 66

1.69

2.72

5.79e-08

IPR035906

MetI-like superfamily

7 of 67

1.68

2.71

5.79e-08

IPR006059

Bacterial extracellular solute-binding protein

3 of 16

1.94

1.19

0.0047

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