STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serCPhosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (370 aa)    
Predicted Functional Partners:
SER45908.1
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.995
SEQ36554.1
Chorismate mutase.
  
  
 0.981
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily.
  
  
 0.974
SEQ65680.1
Phosphoserine phosphatase.
  
 
 0.964
SEQ72279.1
L-threonine synthase.
   
 0.930
SEQ75591.1
4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family.
     
 0.928
SEQ36586.1
Prephenate dehydrogenase.
  
  
 0.926
SEQ75030.1
HAD-superfamily subfamily IB hydrolase, TIGR01490.
  
 
 0.870
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.864
SER10356.1
Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.862
Your Current Organism:
Giesbergeria anulus
NCBI taxonomy Id: 180197
Other names: ATCC 35958, Aquaspirillum anulus, CCUG 49446, G. anulus, IAM 14948, JCM 21430, NBRC 14917, NCIMB 9012, Spirillum anulus
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