STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hscBMolecular chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. (172 aa)    
Predicted Functional Partners:
SEQ37364.1
FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
 
 
 0.999
SEQ37649.1
Ferredoxin, 2Fe-2S.
 
  
 0.991
hscA
Molecular chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
 
 
 0.989
SEQ37409.1
Iron-sulfur cluster assembly protein; Belongs to the HesB/IscA family.
 
 
 0.983
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
 
 0.973
SEQ23990.1
Hsp70 protein.
 
 
 0.926
SEQ24046.1
Molecular chaperone DnaK (HSP70); Belongs to the heat shock protein 70 family.
 
 
 0.925
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.909
SEQ37279.1
Transcriptional regulator, BadM/Rrf2 family.
  
  
 0.905
SEQ41083.1
Hypothetical chaperone protein.
  
 
 0.886
Your Current Organism:
Giesbergeria anulus
NCBI taxonomy Id: 180197
Other names: ATCC 35958, Aquaspirillum anulus, CCUG 49446, G. anulus, IAM 14948, JCM 21430, NBRC 14917, NCIMB 9012, Spirillum anulus
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