STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folDHypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (296 aa)    
Predicted Functional Partners:
glyA
Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.977
A2827_00980
Hypothetical protein; Frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.920
OGZ58730.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.891
OGZ57408.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.839
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
 
 0.806
OGZ57747.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.771
OGZ58591.1
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family.
  
 
 0.771
nusB
Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
  
  
 0.757
OGZ58038.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.753
OGZ58469.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.743
Your Current Organism:
Spechtbacteria bacterium RIFCSPHIGHO201FULL4330
NCBI taxonomy Id: 1802158
Other names: C. Spechtbacteria bacterium RIFCSPHIGHO2_01_FULL_43_30, Candidatus Spechtbacteria bacterium RIFCSPHIGHO2_01_FULL_43_30
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