STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OHD10769.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (156 aa)    
Predicted Functional Partners:
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.941
OHD12256.1
Amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.826
OHD10768.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
OHD10767.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.762
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.671
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.669
OHD14164.1
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.669
OHD06846.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.653
OHD08504.1
Histone deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.650
OHD14240.1
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.634
Your Current Organism:
Spirochaetes bacterium GWB13613
NCBI taxonomy Id: 1802174
Other names: S. bacterium GWB1_36_13, Spirochaetes bacterium GWB1_36_13
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