STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OHD07401.1DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (570 aa)    
Predicted Functional Partners:
nadK
Hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
  
 0.961
A2Y41_01270
Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome; Belongs to the anti-sigma-factor antagonist family.
       0.773
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.767
recX
Hypothetical protein; Modulates RecA activity; Belongs to the RecX family.
  
  
 0.614
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.602
OHD09724.1
Transcription-repair coupling factor; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
   
 0.579
OHD07402.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.576
OHD07403.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.576
murF
Hypothetical protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
  
 0.558
OHD11613.1
Competence/damage-inducible protein A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
 
   
 0.552
Your Current Organism:
Spirochaetes bacterium GWB13613
NCBI taxonomy Id: 1802174
Other names: S. bacterium GWB1_36_13, Spirochaetes bacterium GWB1_36_13
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