STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OHD72084.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (538 aa)    
Predicted Functional Partners:
OHD69976.1
DEAD/DEAH box helicase; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
 
 0.987
OHD68438.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.974
OHD68440.1
Restriction endonuclease subunit R; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.752
OHD72085.1
HNH endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.605
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.600
OHD71326.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
   0.591
OHD72086.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.588
Your Current Organism:
Spirochaetes bacterium RBG164921
NCBI taxonomy Id: 1802195
Other names: S. bacterium RBG_16_49_21, Spirochaetes bacterium RBG_16_49_21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.