STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
secFProtein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (298 aa)    
Predicted Functional Partners:
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 0.999
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
  
 
 0.981
OGL66921.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.979
OGL66950.1
Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
   
 0.972
OGL66724.1
Preprotein translocase subunit SecE; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the SecE/SEC61-gamma family.
   
 0.971
secA
Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
  
 
 0.914
uppP
Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
       0.654
OGL66409.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.649
OGL66410.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.649
OGL66411.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.644
Your Current Organism:
Uhrbacteria bacterium RIFCSPHIGHO201FULL6320
NCBI taxonomy Id: 1802385
Other names: C. Uhrbacteria bacterium RIFCSPHIGHO2_01_FULL_63_20, Candidatus Uhrbacteria bacterium RIFCSPHIGHO2_01_FULL_63_20
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.