node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A2114_00585 | OHA56912.1 | A2114_00585 | A2114_00390 | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | Triose-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.523 |
A2114_00585 | OHA57186.1 | A2114_00585 | A2114_00025 | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | Hypothetical protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.935 |
A2114_00585 | glyA | A2114_00585 | A2114_01925 | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.608 |
A2114_00585 | ileS | A2114_00585 | A2114_01900 | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | Hypothetical protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.507 |
A2114_00585 | nusB | A2114_00585 | A2114_01765 | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | Ribonuclease III; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.879 |
A2114_00585 | rpoB | A2114_00585 | A2114_02815 | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.590 |
A2114_00585 | rpsJ | A2114_00585 | A2114_02345 | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.752 |
OHA56912.1 | A2114_00585 | A2114_00390 | A2114_00585 | Triose-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | 0.523 |
OHA56912.1 | glyA | A2114_00390 | A2114_01925 | Triose-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.536 |
OHA56912.1 | ileS | A2114_00390 | A2114_01900 | Triose-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.866 |
OHA56912.1 | nusB | A2114_00390 | A2114_01765 | Triose-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonuclease III; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.894 |
OHA56912.1 | rpoB | A2114_00390 | A2114_02815 | Triose-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.496 |
OHA56912.1 | rpsJ | A2114_00390 | A2114_02345 | Triose-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.424 |
OHA57154.1 | nusB | A2114_02905 | A2114_01765 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonuclease III; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.874 |
OHA57186.1 | A2114_00585 | A2114_00025 | A2114_00585 | Hypothetical protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | 0.935 |
OHA57186.1 | glyA | A2114_00025 | A2114_01925 | Hypothetical protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.820 |
OHA57186.1 | nusB | A2114_00025 | A2114_01765 | Hypothetical protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonuclease III; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.882 |
OHA57186.1 | rpoB | A2114_00025 | A2114_02815 | Hypothetical protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.403 |
OHA57186.1 | rpsJ | A2114_00025 | A2114_02345 | Hypothetical protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.999 |
OHA57726.1 | glyA | A2114_02510 | A2114_01925 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.844 |