STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDY37871.1[E] COG0287 Prephenate dehydrogenase. (276 aa)    
Predicted Functional Partners:
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 0.993
hisC
Aminotransferases class-I; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase.
  
 
 0.966
pheA
Chorismate mutase - Prephenate dehydratase; [E] COG0077 Prephenate dehydratase.
 
 0.942
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 0.911
EDY37754.1
Isochorismate synthase; [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I.
     
 0.874
EDY38880.1
Threonine-phosphate decarboxylase; [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.
  
 
 0.864
EDY37304.1
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
     
 0.864
EDY39597.1
[E] COG0436 Aspartate/tyrosine/aromatic aminotransferase.
    
 0.861
panC/cmk
Bifunctional pantoate ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family.
 
 
 0.774
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
  
 0.766
Your Current Organism:
Cyanobium sp. PCC7001
NCBI taxonomy Id: 180281
Other names: Anacystis marina 6, C. sp. PCC 7001, Cyanobium sp. PCC 7001, Synechococcus sp. PCC 7001
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