STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCA_000797495_01291Unannotated protein. (358 aa)    
Predicted Functional Partners:
comM
Unannotated protein.
 
 0.982
topA
Unannotated protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.945
GCA_000797495_02043
Unannotated protein.
 
 
 0.910
GCA_000797495_05216
Unannotated protein.
 
  
 0.849
barA_4
Unannotated protein.
  
  
 0.759
comC_2
Unannotated protein.
 
  
 0.720
GCA_000797495_05465
Unannotated protein; Belongs to the UPF0102 family.
 
    0.705
comC_1
Unannotated protein.
  
  
 0.683
ruvB
Unannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
 
     0.649
rpfG_2
Unannotated protein.
  
    0.644
Your Current Organism:
Robinsoniella peoriensis
NCBI taxonomy Id: 180332
Other names: CCUG 48729, Clostridium sp. CCUG 52336, NRRL B-23985, R. peoriensis, Robinsoniella peoriensis Cotta et al. 2009, strain PPC31, swine fecal bacterium FPC47, swine fecal bacterium FPC50, swine manure pit bacterium PPC108, swine manure pit bacterium PPC31, swine manure pit bacterium PPC37, swine manure pit bacterium PPC44
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.