STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C1646_641836ERCC4 domain-containing protein. (517 aa)    
Predicted Functional Partners:
C1646_702891
AA_TRNA_LIGASE_II domain-containing protein.
   
 0.981
C1646_624690
Restriction endonuclease type II-like protein.
   
 0.971
C1646_772910
DUF1767 domain-containing protein.
    
 0.964
C1646_733600
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.964
C1646_744218
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.955
C1646_626549
XPA protein C-terminus-domain-containing protein.
    
 0.955
C1646_702226
P-loop containing nucleoside triphosphate hydrolase protein.
   
 0.955
C1646_756342
Uncharacterized protein.
   
 0.954
C1646_621768
PIN domain-like protein.
   
 0.952
C1646_624050
ERCC4 domain-containing protein.
  
 
 0.950
Your Current Organism:
Rhizophagus sp. MUCL43196
NCBI taxonomy Id: 1803374
Other names: R. sp. MUCL 43196, Rhizophagus sp. MUCL 43196, Rhizophagus sp. MUCL-43196
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.