KYK37515.1 protein (Theionarchaea archaeon) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Score

KYK37515.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (255 aa)

Predicted Functional Partners:

AYK19_06965

0.817

KYK28484.1

0.508

KYK29346.1

0.452

KYK37595.1

0.427

KYK35123.1

0.419

Your Current Organism:

Theionarchaea archaeon

NCBI taxonomy Id: 1803814
Other names: T. archaeon DG-70-1, Theionarchaea archaeon DG-70-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AYK19_06965	KYK37515.1	AYK19_06965	AYK19_06970	Hypothetical protein; Incomplete; too short partial abutting assembly gap; missing start; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.817
KYK28484.1	KYK29346.1	AYK19_20875	AYK19_19890	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.577
KYK28484.1	KYK35123.1	AYK19_20875	AYK19_11210	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.520
KYK28484.1	KYK37515.1	AYK19_20875	AYK19_06970	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.508
KYK29346.1	KYK28484.1	AYK19_19890	AYK19_20875	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.577
KYK29346.1	KYK37515.1	AYK19_19890	AYK19_06970	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.452
KYK35123.1	KYK28484.1	AYK19_11210	AYK19_20875	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.520
KYK35123.1	KYK37515.1	AYK19_11210	AYK19_06970	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.419
KYK37515.1	AYK19_06965	AYK19_06970	AYK19_06965	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Incomplete; too short partial abutting assembly gap; missing start; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.817
KYK37515.1	KYK28484.1	AYK19_06970	AYK19_20875	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.508
KYK37515.1	KYK29346.1	AYK19_06970	AYK19_19890	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.452
KYK37515.1	KYK35123.1	AYK19_06970	AYK19_11210	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.419
KYK37515.1	KYK37595.1	AYK19_06970	AYK19_06875	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.427
KYK37595.1	KYK37515.1	AYK19_06875	AYK19_06970	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.427

Network Stats

number of nodes:

11

number of edges:

43

average node degree:

7.82

avg. local clustering coefficient:

0.882

expected number of edges:

29

PPI enrichment p-value:

0.0081

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006457

Protein folding

3 of 16

1.68

0.93

0.0130

GO:0006412

Translation

5 of 99

1.11

0.71

0.0130

GO:0010467

Gene expression

7 of 222

0.9

0.65

0.0058

GO:0044260

Cellular macromolecule metabolic process

7 of 418

0.63

0.38

0.0387

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051082

Unfolded protein binding

3 of 7

2.04

1.54

0.0010

GO:0003735

Structural constituent of ribosome

5 of 55

1.36

1.19

0.00090

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

5 of 58

1.34

1.31

0.00025

GO:0005622

Intracellular anatomical structure

10 of 896

0.45

0.36

0.0023

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:448

Unfolded protein binding, and Protein homodimerization activity

3 of 8

1.98

1.65

0.00052

CL:95

Mixed, incl. Translation, and Bacterial secretion system

10 of 200

1.1

1.43

2.94e-08

CL:115

Ribosome

5 of 67

1.28

1.19

0.00041

CL:104

Ribosome, and ATP synthesis

6 of 101

1.18

1.1

0.00034

CL:237

Structural constituent of ribosome

2 of 5

2.01

1.05

0.0098

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

5 of 59

1.33

1.3

0.00025

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

4 of 44

1.36

0.96

0.0054

GOCC:0022625

Cytosolic large ribosomal subunit

2 of 5

2.01

0.93

0.0171

GOCC:0043232

Intracellular non-membrane-bounded organelle

5 of 124

1.01

0.7

0.0083

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

5 of 60

1.33

1.23

0.00045

KW-0687

Ribonucleoprotein

5 of 60

1.33

1.23

0.00045

KW-0346

Stress response

2 of 8

1.8

0.76

0.0348

KW-0699

rRNA-binding

3 of 41

1.27

0.65

0.0348

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