STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OLD11975.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (631 aa)    
Predicted Functional Partners:
OLD11071.1
DNA topoisomerase I; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.897
rpl1
50S ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
    
 0.844
OLD11751.1
asparagine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.806
OLD13866.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.802
OLD10533.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.783
pcn
Proliferating cell nuclear antigen (pcna); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
  
 
 0.774
fen-2
protein-L-isoaspartate O-methyltransferase; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision [...]
  
 0.771
OLD13800.1
Flap endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.768
OLD11449.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.754
OLD13081.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.739
Your Current Organism:
Crenarchaeota archaeon 13140CM35210
NCBI taxonomy Id: 1805095
Other names: C. archaeon 13_1_40CM_3_52_10, Crenarchaeota archaeon 13_1_40CM_3_52_10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.