STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OLE02484.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (156 aa)    
Predicted Functional Partners:
OLE09308.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family.
    
 0.723
OLE02485.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.693
OLE02489.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytochrome P450 family.
     
 0.673
aroK
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
    
 0.473
OLE08809.1
Serine hydroxymethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.453
OLE09173.1
Hypothetical protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
    
 0.441
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
    
 0.438
OLE08803.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
  
 0.411
Your Current Organism:
Ktedonobacter sp. 13120CM45311
NCBI taxonomy Id: 1805225
Other names: K. sp. 13_1_20CM_4_53_11, Ktedonobacter sp. 13_1_20CM_4_53_11
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.