STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OIP74514.1serine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)    
Predicted Functional Partners:
lysS
lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
    0.806
pheS
phenylalanine--tRNA ligase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
  
 
 0.798
OIP74513.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.797
OIP74515.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.739
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.727
secA
Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
     
 0.723
argS
arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.682
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
  
 
 0.673
hisS
histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.654
cysS
cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.625
Your Current Organism:
Pacebacteria bacterium CG2303639
NCBI taxonomy Id: 1805300
Other names: C. Pacebacteria bacterium CG2_30_36_39, Candidatus Pacebacteria bacterium CG2_30_36_39
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