NEDG_00226 protein (Nematocida displodere) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NEDG_00226

DNA helicase MCM8; Belongs to the MCM family. (661 aa)

Predicted Functional Partners:

NEDG_00761

0.985

NEDG_02154

0.985

NEDG_01875

0.985

MCM7

0.984

NEDG_00281

0.960

NEDG_00808

0.955

NEDG_00347

0.947

NEDG_00554

0.919

NEDG_02201

0.907

NEDG_00427

0.906

Your Current Organism:

Nematocida displodere

NCBI taxonomy Id: 1805483
Other names: N. displodere, Nematocida displodere Luallen et al. 2016, Nematocida sp. JUm2807

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	NEDG_00226	A0A177EEU5	A0A177EJV9	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase MCM8; Belongs to the MCM family.	0.984
MCM7	NEDG_00281	A0A177EEU5	A0A177EJC4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase MCM9; Belongs to the MCM family.	0.979
MCM7	NEDG_00347	A0A177EEU5	A0A177EL98	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Origin recognition complex subunit 1.	0.989
MCM7	NEDG_00427	A0A177EEU5	A0A177ELH3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DBF4-type domain-containing protein.	0.952
MCM7	NEDG_00554	A0A177EEU5	A0A177ED16	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.997
MCM7	NEDG_00761	A0A177EEU5	A0A177ECT1	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	NEDG_00808	A0A177EEU5	A0A177ECK1	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	NEDG_01875	A0A177EEU5	A0A177EI02	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA replication licensing factor MCM5; Belongs to the MCM family.	0.999
MCM7	NEDG_02154	A0A177EEU5	A0A177EH90	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA replication licensing factor MCM3; Belongs to the MCM family.	0.999
MCM7	NEDG_02201	A0A177EEU5	A0A177EIM2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Cell division control protein 7; Belongs to the protein kinase superfamily.	0.971
NEDG_00226	MCM7	A0A177EJV9	A0A177EEU5	DNA helicase MCM8; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.984
NEDG_00226	NEDG_00281	A0A177EJV9	A0A177EJC4	DNA helicase MCM8; Belongs to the MCM family.	DNA helicase MCM9; Belongs to the MCM family.	0.960
NEDG_00226	NEDG_00347	A0A177EJV9	A0A177EL98	DNA helicase MCM8; Belongs to the MCM family.	Origin recognition complex subunit 1.	0.947
NEDG_00226	NEDG_00427	A0A177EJV9	A0A177ELH3	DNA helicase MCM8; Belongs to the MCM family.	DBF4-type domain-containing protein.	0.906
NEDG_00226	NEDG_00554	A0A177EJV9	A0A177ED16	DNA helicase MCM8; Belongs to the MCM family.	Uncharacterized protein.	0.919
NEDG_00226	NEDG_00761	A0A177EJV9	A0A177ECT1	DNA helicase MCM8; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.985
NEDG_00226	NEDG_00808	A0A177EJV9	A0A177ECK1	DNA helicase MCM8; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.955
NEDG_00226	NEDG_01875	A0A177EJV9	A0A177EI02	DNA helicase MCM8; Belongs to the MCM family.	DNA replication licensing factor MCM5; Belongs to the MCM family.	0.985
NEDG_00226	NEDG_02154	A0A177EJV9	A0A177EH90	DNA helicase MCM8; Belongs to the MCM family.	DNA replication licensing factor MCM3; Belongs to the MCM family.	0.985
NEDG_00226	NEDG_02201	A0A177EJV9	A0A177EIM2	DNA helicase MCM8; Belongs to the MCM family.	Cell division control protein 7; Belongs to the protein kinase superfamily.	0.907