Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN08_1561HTH-type transcriptional regulator. (344 aa)    
Predicted Functional Partners:
RN08_1559
Monooxygenase.
 
   
 0.800
RN08_1560
Cytochrome P450 Cyp132.
     
 0.744
RN08_4121
AraC/XylS family transcriptional regulator.
  
   
0.719
RN08_3394
HTH-type transcriptional regulator VirS.
  
   
0.717
RN08_0697
Ribonuclease VapC30.
   
    0.716
RN08_0307
Transcriptional regulator.
   
  
 0.715
RN08_1916
Hypothetical protein.
  
  
 0.708
RN08_1333
ECF RNA polymerase sigma factor SigI.
  
  
 0.704
RN08_3489
TetR family transcriptional regulator.
   
  
 0.704
RN08_2177
Antitoxin ParD1.
   
    0.703
Your Current Organism:
Mycobacterium tuberculosis variant microti
NCBI taxonomy Id: 1806
Other names: ATCC 19422, CIP 104256, M. tuberculosis variant microti, Mycobacterium microti, Mycobacterium muris, Mycobacterium tuberculosis var. muris, NCTC 8710
Server load: low (22%) [HD]