Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN08_22486-phosphofructokinase PfkB. (340 aa)    
Predicted Functional Partners:
RN08_0408
Fructose-bisphosphate aldolase.
  
 
 0.985
RN08_2249
Hypothetical protein.
 
  
 0.985
RN08_2247
Universal stress protein.
  
  
 0.979
RN08_1053
Glucose-6-phosphate isomerase.
    
 0.976
RN08_1234
Fructose 1,6-bisphosphatase.
     
 0.967
RN08_1619
Transaldolase.
  
 
 0.960
RN08_3322
6-phosphofructokinase.
  
  
 0.946
RN08_1620
Transketolase.
  
 
 0.920
RN08_3591
Mannose-6-phosphate isomerase.
    
 0.920
RN08_2251
NAD(P)H nitroreductase acg.
  
  
 0.901
Your Current Organism:
Mycobacterium tuberculosis variant microti
NCBI taxonomy Id: 1806
Other names: ATCC 19422, CIP 104256, M. tuberculosis variant microti, Mycobacterium microti, Mycobacterium muris, Mycobacterium tuberculosis var. muris, NCTC 8710
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