STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RN08_2489Pyruvate dehydrogenase E1 component. (504 aa)    
Predicted Functional Partners:
RN08_2488
Pyruvate dehydrogenase E1 component.
  
  0.998
RN08_0515
Dihydrolipoamide dehydrogenase.
  
 
 0.987
RN08_2766
Branched-chain keto acid dehydrogenase E2 component.
  
 0.985
RN08_1396
Multifunctional 2-oxoglutarate dehydrogenase E1 component /2-oxoglutarate dehydrogenase dihydrolipoyllysine-residue succinyltransferase.
 
 0.972
RN08_2768
Branched-chain keto acid dehydrogenase E1 component subunit alpha.
    
 0.972
RN08_1790
Pyruvate kinase.
  
 
 0.965
RN08_2767
Branched-chain keto acid dehydrogenase E1 component subunit beta.
     
 0.961
RN08_2459
Pyruvate dehydrogenase E2 component dihydrolipoamide acyltransferase.
 
 0.945
RN08_2721
2-oxoglutarate oxidoreductase subunit KorA.
    
 0.926
RN08_2586
Malate oxidoreductase.
    
 0.924
Your Current Organism:
Mycobacterium tuberculosis variant microti
NCBI taxonomy Id: 1806
Other names: ATCC 19422, CIP 104256, M. tuberculosis variant microti, Mycobacterium microti, Mycobacterium muris, Mycobacterium tuberculosis var. muris, NCTC 8710
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.