Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN08_3198Signal peptidase. (294 aa)    
Predicted Functional Partners:
RN08_3197
Ribonuclease HII.
 
  
 0.943
RN08_2667
GTP-binding protein LepA.
  
 
 0.881
RN08_3199
50S ribosomal protein L19.
  
  
 0.850
RN08_4263
Glutamate synthase large subunit.
     
 0.741
RN08_3196
Hypothetical protein.
       0.711
RN08_0813
Preprotein translocase SecY.
  
 
 0.691
RN08_4321
Membrane protein insertase YidC.
 
  
 0.647
RN08_2867
Protein translocase subunit SecD.
  
  
 0.630
RN08_2321
Sec-independent protein translocase transmembrane protein TatC.
 
  
 0.624
RN08_3576
Protein translocase subunit SecA.
 
   
 0.606
Your Current Organism:
Mycobacterium tuberculosis variant microti
NCBI taxonomy Id: 1806
Other names: ATCC 19422, CIP 104256, M. tuberculosis variant microti, Mycobacterium microti, Mycobacterium muris, Mycobacterium tuberculosis var. muris, NCTC 8710
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