Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN08_3209Serine/threonine-protein kinase PknI. (269 aa)    
Predicted Functional Partners:
RN08_3207
TetR family HTH-type transcriptional regulator.
     
 0.559
RN08_3208
D-amino acid aminohydrolase.
     
 0.536
RN08_1417
Hypothetical protein.
  
 
 0.455
RN08_0023
Phosphoserine/threonine phosphatase PstP.
  
 
 0.453
RN08_0025
FHA domain-containing protein FhaA.
   
 
 0.437
RN08_2032
Glycogen accumulation regulator GarA.
   
 
 0.437
RN08_1941
ABC transporter ATP-binding protein/permease.
  
 
 0.419
RN08_3707
Hypothetical protein.
  
 
 0.419
RN08_3212
Signal recognition particle protein.
  
  
 0.400
Your Current Organism:
Mycobacterium tuberculosis variant microti
NCBI taxonomy Id: 1806
Other names: ATCC 19422, CIP 104256, M. tuberculosis variant microti, Mycobacterium microti, Mycobacterium muris, Mycobacterium tuberculosis var. muris, NCTC 8710
Server load: low (18%) [HD]