Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RN08_32963-isopropylmalate dehydratase small subunit. (198 aa)    
Predicted Functional Partners:
RN08_3297
3-isopropylmalate dehydratase large subunit.
 0.999
RN08_3305
3-isopropylmalate dehydrogenase.
 
 
 0.999
RN08_4092
2-isopropylmalate synthase.
 
 
 0.998
RN08_3298
Transcriptional regulator.
 
  
 0.934
RN08_3313
Ketol-acid reductoisomerase.
 
  
 0.916
RN08_3314
Acetolactate synthase small subunit.
 
  
 0.898
RN08_3829
4-hydroxy-2-oxovalerate aldolase MhpE.
 
 
 0.866
RN08_3910
4-hydroxy-2-oxovalerate aldolase.
  
 
 0.846
RN08_2586
Malate oxidoreductase.
  
 
 0.834
RN08_1790
Pyruvate kinase.
  
 
 0.825
Your Current Organism:
Mycobacterium tuberculosis variant microti
NCBI taxonomy Id: 1806
Other names: ATCC 19422, CIP 104256, M. tuberculosis variant microti, Mycobacterium microti, Mycobacterium muris, Mycobacterium tuberculosis var. muris, NCTC 8710
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