Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN08_3540TetR family transcriptional regulator. (228 aa)    
Predicted Functional Partners:
RN08_0940
Nitrate/nitrite response transcriptional regulator NarL.
   
    0.640
RN08_1311
Transcriptional regulator.
   
  
 0.607
RN08_3075
Transcriptional repressor SirR.
   
  
 0.606
RN08_2177
Antitoxin ParD1.
   
    0.603
RN08_3539
Hypothetical protein.
       0.500
RN08_0307
Transcriptional regulator.
   
  
 0.494
RN08_0475
Hypothetical protein.
      
 0.481
RN08_1292
Transcriptional regulator.
  
  
 0.434
RN08_3328
Hypothetical protein.
  
 
   0.401
Your Current Organism:
Mycobacterium tuberculosis variant microti
NCBI taxonomy Id: 1806
Other names: ATCC 19422, CIP 104256, M. tuberculosis variant microti, Mycobacterium microti, Mycobacterium muris, Mycobacterium tuberculosis var. muris, NCTC 8710
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