Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RN08_4151Two component transcriptional regulator TcrX. (234 aa)    
Predicted Functional Partners:
RN08_4150
Two component sensor kinase TcrY.
 
 0.987
RN08_1160
Two component sensor histidine kinase TrcS.
 
 0.932
RN08_0544
Two component sensor histidine kinase SenX3.
 
 0.915
RN08_1004
Two component sensor histidine kinase PrrB.
 
 0.913
RN08_0847
Two component system response sensor kinase PhoR.
 
 0.903
RN08_0673
Two component sensor kinase HK1.
 
 0.886
RN08_3581
Two component sensory histidine kinase MtrB.
 
 0.875
RN08_1095
Two component histidine-protein kinase/phosphatase MprB.
 
 0.868
RN08_1152
Sensor protein KdpD; Overlaps another CDS with the same product name.
 
 0.828
RN08_0674
Two component sensor kinase HK2.
 
 0.791
Your Current Organism:
Mycobacterium tuberculosis variant microti
NCBI taxonomy Id: 1806
Other names: ATCC 19422, CIP 104256, M. tuberculosis variant microti, Mycobacterium microti, Mycobacterium muris, Mycobacterium tuberculosis var. muris, NCTC 8710
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