Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
RN08_4313Thioredoxin reductase. (335 aa)    
Predicted Functional Partners:
RN08_4314
Thioredoxin TrxC.
 
 0.998
RN08_1646
Thioredoxin.
 
 0.992
RN08_2694
Alkyl hydroperoxide reductase subunit C.
  
 
 0.919
RN08_1639
Cysteine desulfurase.
  
 
  0.909
RN08_2036
Glycine dehydrogenase.
   
 
 0.861
RN08_1645
Thioredoxin TrxA.
  
 
 0.832
RN08_1483
Thioredoxin.
  
 
 0.831
RN08_3147
Mycothione reductase.
 
 0.793
RN08_0912
Thioredoxin ThiX.
  
 
 0.750
RN08_4312
anti-sigma-M factor RsmA.
       0.747
Your Current Organism:
Mycobacterium tuberculosis variant microti
NCBI taxonomy Id: 1806
Other names: ATCC 19422, CIP 104256, M. tuberculosis variant microti, Mycobacterium microti, Mycobacterium muris, Mycobacterium tuberculosis var. muris, NCTC 8710
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